It is easy nowadays to summon a car to deliver you to a brewery or from one brewery to another. You also will find running clubs associated with a brewery. And if you really want to take your life in your hands, you can bike. I hate to run but even I would take that over bicycling.
My choice A is walking and whilst in Denver, I was able to saunter from a brewery, to another and then another. The next day, I walked around a lake from one corner to another to visit two breweries. I miss being able to do that in Los Angeles as there are relatively few neighborhoods where multiple breweries exist.
Torrance on Del Amo is one. Arts District in DTLA is a second. Both have their charms and drawbacks. And maybe if economic times improve or a new gust of brewery wind hits the sails we will be able to create more walkable beer paths.